I Introduction
1 Epidemiology and Prevention 3
2 Pharmacokinetics 13
3 Psychiatric Assessment and Management 41
II General Approach to the Poisoned Patient
4 Initial Evaluation and Management of the Poisoned Patient 63
5 Enhancement of Elimination 165
6 Toxicology Screening: Role of the Clinical Laboratory 181
7 Electrocardiographic Manifestations of Toxic Agents 191
8 Special Considerations in Pregnancy 199
9 Pediatric Poisonings 209
10 Special Considerations in the Geriatric Patient 221
11 Hemoglobin Toxins 227
12 Anion and Osmolar Gaps 239
13 Nontoxic Ingestions 251
14 Chemical Warfare Agents 255
III Industrial and Household Toxicology
15 Ethylene Glycol, Methanol, and Isopropyl Alcohol 269
16 Aldehydes, Ketones, Ethers, and Esters 287
17 Hydrocarbons 299
18 Nitrates and Nitrites 315
19 Hydrogen Fluoride 325
20 Acids and Alkalies 335
21 Phenols 355
22 Lead Toxicity 363
23 Cadmium, Mercury, and Arsenic 379
24 Metals: Iron Intoxication 391
25 Insecticides and Pesticides 401
26 Herbicides and Fungicides 415
27 Rodenticides 425
28 Toxicity of Household Products 437
29 Industrial Exposure to Toxins 535
IV Medical Toxicology
30 Salicylates 551
31 Acetaminophen 559
32 Nonsteroidal Antiinflammatories 581
33 Antiinfective Agents 589
34 Laxative Abuse 601
35 Hypervitaminosis 607
36 Anticoagulants 627
37 Poisoning by Antidysrhythmic Drugs 637
38 Angiotensin Converting Enzyme Inhibitors 681
39 Beta-Blockers 687
40 Calcium Channel Blockers 695
41 Clonidine 703
42 Digoxin 707
43 Disulfiram 723
44 Antihistamines 731
45 Hypoglycemic Agents 739
46 Skeletal Muscle Relaxers 745
47 Colchicine 751
48 Isoniazid 755
49 Anticonvulsants 763
50 Methylxanthines: Theophylline and Caffeine 775
51 Quinine 785
52 Ergot Alkaloids 791
53 Thyroid Hormones 799
V Psychiatric Drugs
54 Antipsychotic Drugs 805
55 Tricyclic Antidepressants 817
56 New Antidepressants 829
57 Monoamine Oxidase Inhibitors 837
58 Lithium 845
VI Drugs of Abuse
59 Opioids 855
60 Sedative-Hypnotics 863
61 Hallucinogens 877
62 Phencyclidine 885
63 Marijuana 893
64 Amphetamines 899
65 Cocaine 903
66 Alcohol Intoxication 909
67 Nicotine 919
68 Abuse of Volatile Substances 925
69 Sports Drugs of Abuse 933
70 Drug Withdrawal Syndromes 947
VII Environmental Toxins
71 Nitrogen Oxides and Silo-Filler's Disease 959
72 Hydrogen Sulfide 965
73 Cyanide 969
74 Carbon Monoxide Poisoning 979
75 Ionizing Radiation 991
76 Foodborne Toxins 997
77 Foreign Bodies 1007
78 PCBs and Dioxins 1015
VIII Animal Toxicology
79 Arthropod Envenomation 1027
80 Reptilian Envenomation 1035
81 Amphibian Toxins 1049
82 Marine Toxins 1055
IX Plant Toxicology
83 Systemic Poisonous Plant Intoxication 1067
84 Mushroom Poisoning 1081
85 Poisoning from Herbs and Related Products 1087
86 Differential Diagnosis of Poisonings 1103
Subject Index 1217