Intracranial Metastases: Current Management Strategies > Hematology. Oncology

This is the first comprehensive textbook on intracranial metastases in over 20 years with an update on current methods for their management, including the use of newer technologies.
Each of the various histological types of cancer metastasizing to the brain is presented separately in a detailed analysis and discussion.
This volume includes a consideration of the epidemiology of brain metastases and the quality of life in patients who have them.
Special topics not previously covered are reviewed, including metastasis to the skull base and strategies for preventing cancer from metastasizing to the brain.
A novel feature is a chapter devoted to the use of recent techniques such as functional magnetic resonance (MR) imaging, MR spectroscopy (metabolite mapping), and dynamic susceptibility contrast imaging (regional cerebral blood volume mapping) to characterize brain metastases in terms of the sensorimotor perturbations they produce, their metabolic response to therapy, and their degree of vascularization, respectively.

I. General
1 Management of Intracranial Metastases: History
Deric Minwoo Park, MD and Jerome B. Posner, MD
2 The Epidemiology of Brain Metastasis
Dima Suki, PhD
3 The Biology of Brain Metastasis
Isaiah J. Fidler, DVM, PhD
4 Brain Metastases: Histopathologic Evaluation and Diagnostic Pitfalls
Teresa Ribalta, MD, PhD and Gregory N. Fuller, MD, PhD
5 Imaging of Metastatic Tumors of the Brain
Norman E. Leeds, MD, Edward F. Jackson, PhD, MS, BS, and Ashok J. Kumar, MD
II. Principles of Therapy
6 Intracranial Metastases: Medical Management and Prognostic Factors
Susanne M. Arnold, MD and Roy A. Patchell, MD
7 Surgical Management and Techniques
Frederick F. Lang, MD, FACS
8 Whole Brain Radiation Therapy
Ritsuko Komaki, MD, FACR and Eric Chang, MD
9 Radiosurgery for Single and Multiple Brain Metastases
Minesh P. Mehta, MD and Ivo Tremont-Lukats, MD
10 Stereotactic Radiation of Intracranial Metastases
Griffith R. Harsh IV, MD
11 Chemotherapy for Brain Metastases
Sigmund H. Hsu, MD and W. K. Alfred Yung, MD
III. Specific Tumor Sites
12 Metastatic Lung Cancer
James L. Frazier, ScB, Ira M. Garonzik, MD, and Laurence D. Rhines, MD
13 Current Management Strategies in Intracranial Breast Cancer Metastasis
Stacy Moulder, MD, David H. Johnson, MD and Steven A. Toms, MD, MPH
14 Management of Brain Metastasis in Malignant Melanoma Patients
Andrew A. Kanner, MD and Gene H. Barnett, MD
15 Brain Metastases from Renal Cell Carcinoma
Fadi Hanbali, MD and Jeffrey S. Weinberg, MD
16 Metastatic Colorectal Carcinoma
Vijayabalan Balasingam MD, PhD, FRCS (C) and Ian E. McCutcheon MD, FRCS (C)
17 Brain Metastasis from Cancer of an Unknown Primary Site
Robert J. Bohinski, MD, PhD and Ronald E. Warnick, MD
18 Leptomeningeal Carcinomatosis: Diagnosis and Management
Morris D. Groves, Jr., MD, JD
19 Brain Metastases from Gynecologic Cancers
Maciej S. Lesniak, MD and Alessandro Olivi, MD
20 Brain Metastases from Genitourinary Cancer: Germ Cell, Testicular, Prostate and Bladder Cancer
Philip V. Theodosopoulos, MD, James L. Rubenstein, MD, and Michael W. McDermott, MD
21 Brain Metastasis from Upper Gastrointestinal Tract Cancers: Esophageal, Gastric, Hepatic, Gallbladder, and Pancreatic
Jeffrey S. Weinberg, MD, Renato Lenzi, MD, and Ziya L. Gokaslan, MD, FACS
22 Brain Metastases From Thyroid Carcinoma and Other Endocrine Malignancies
Rena Vassilopoulou-Sellin, MD
23 Brain Metastasis From Sarcomas
Andrew E. Sloan, MD and Michael Kraut, MD
IV. Special Considerations
24 Metastatic Tumors of the Skull Base
Fadi Hanbali MD and Franco DeMonte MD, FRCSC, FACS
25 Neuropsychological Impact of the Brain Metastasis and its Treatment
Anne E. Kayl, PhD and Christina A. Meyers, PhD, ABPP
26 Adjuvant Approaches for Preventing Brain Metastases
David G. Menter, PhD, Anita L. Sabichi, MD, and Scott M. Lippman, MD
27 Intracranial Metastases: Management Guidelines and Decision Making
Syed Enam, MD and Jack P. Rock, MD

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