Principles and Practice of Sleep Medicine(2volume Set)7/e > Respiratory Medicine

Offering today’s most authoritative, comprehensive coverage of sleep disorders, Kryger’s Principles and Practice of Sleep Medicine, 7th Edition, is a must-have resource for sleep medicine specialists, fellows, trainees, and technicians, as well as pulmonologists, neurologists, and other clinicians who see patients with sleep-related issues. It provides a solid understanding of underlying basic science as well as complete coverage of emerging advances in management and treatment for a widely diverse patient population. Evidence-based content, hundreds of full-color illustrations, and a wealth of additional resources online help you make well-informed clinical decisions and offer your patients the best possible care.

Key Features

Contains new chapters on sleep in intersex and transgender individuals; sleep telemedicine and remote PAP adherence monitoring; and sleep and the menstrual cycle, as well as increased coverage of treatment and management of pediatric patients.

Includes expanded sections on pharmacology, sleep in individuals with other medical disorders, and methodology.

Discusses updated treatments for sleep apnea and advancements in CPAP therapy.

Offers access to 95 video clips online, including expert interviews and sleep study footage of various sleep disorders.

Meets the needs of practicing clinicians as well as those preparing for the sleep medicine fellowship examination or recertification exams, with more than 950 self-assessment questions, answers, and rationales online.

Enhanced eBook version included with purchase. Your enhanced eBook allows you to access all of the text, figures, and references from the book on a variety of devices.

Author Information

By Meir H. Kryger, MD. FRCPC, Professor, Pulmonary, Critical Care, and Sleep Medicine, Yale School of Medicine, New Haven, Connecticut

1        History of Sleep Physiology and Medicine
2        Normal Human Sleep: An Overview
3        Normal Aging
4        Daytime Sleepiness and Alertness
5        Sleep Deprivation
6        Introduction/Defining sleep
          Introduction
7        Neural Control of Sleep in Mammals
8        REM Sleep control and function
9        Deep-Brain Imaging of Brain Neurons and Glia during Sleep
10      Evolution of mammalian sleep
11      Sleep in Non-mammalian Vertebrates
12      Introduction: Genetics and Genomics of Sleep
13      Genetics and Genomics of Circadian Clocks
14      Genetics and Genomic Basis of Sleep in Simple Model Organisms
15      Genetics and Genomic Basis of Sleep in Rodents
16      Genetics and Genomic Basis of Sleep in Healthy Humans
17      Genetics and Genomic Basis of Sleep Disorders in Humans
18      Introduction to Physiology in Sleep
19      What Neuroimaging Reveals About the Brain Areas Generating, Maintaining and Regulating Sleep
20      Cardiovascular Physiology and Coupling with Respiration: Central and Autonomic Regulation
21      Cardiovascular Physiology: Autonomic Control in Health and in Sleep Disorders
22       Respiratory Physiology: Central Neural Control of Respiratory Neurons and Motoneurons during Sleep
23       Respiratory Physiology: Understanding the Control of Ventilation
24       Physiology of the Upper and Lower Airways
25       Respiratory Physiology: Sleep at High Altitudes
26       Sleep and Host Defense
27       Endocrine Physiology in Relation to Sleep and Sleep Disturbances
28       Thermoregulation in Sleep and Hibernation
29       Memory Processing in Relation to Sleep
30       Sensory and Motor Processing during Sleep and Wakefulness
31       Local and Use Dependent Aspects of Sleep
32       Pathophysiology of Sleep-Wake Disturbances after Traumatic Brain Injury
33       Introduction
34       Master Circadian Clock and Master Circadian Rhythm
35       Anatomy of the Mammalian Circadian System
36       Physiology of the Mammalian Circadian System
37       Human Circadian Timing System and Sleep-Wake Regulation
38       Sleep Homeostasis and Models of Sleep Regulation
39       Circadian Rhythms in Sleepiness, Alertness, and Performance
40       Central and Peripheral Circadian Clocks
41       Circadian Dysregulation and Cardiometabolic and Immune Health
42       Circadian Dysregulation in Brain Aging and Neuropsychiatric Health
43       Circadian Disorders of the Sleep-Wake Cycle
           Introduction
44       Introduction
45       Adenosine
46       Role of catecholamines in sleep-wake control in health and disease
47       Cholinergics
47       GABA
48       Histamine
49       Hypocretin/orexin
50       Serotonin and sleep
51       Melatonin
52       Opioids
53       Drugs That Disturb Sleep and Wakefulness
54       Introduction
55       Why We Dream
56       Dream Content: Quantitative Findings
57       EEG Correlates of Sucessful Dream Recall
58       The Neurobiology of Dreaming
59       Lucid Dreaming
60       What is the Function of Nightmares?
61       Dreams and Nightmares in Posttraumatic Stress Disorder
62       Incorporation of Waking Experiences into Dreams
63       Emotion, Motivation, and Reward in Relation to Dreaming
64       Dreaming during Pregnancy
65       Approach to the Patient with Disordered Sleep
66       Cardinal Manifestations of Sleep Disorders
67       Physical Examination of the Sleep Medicine Patient
68       Use of Clinical Tools and Tests in Sleep Medicine
69       Classification of Sleep Disorders
70       Epidemiology of Sleep Disorders
71       Sleep Medicine, Public Policy, and Public Health
72       Introduction
           Introduction
73       Sleep Forensics: Criminal Culpability for Sleep-Related Violence
74       Legal Obligations of Persons Who Have Sleep Disorders or Who Treat or Hire Them
75       Legal Aspects of Fatigue- and Safety-Sensitive Professions
76       Sleep Medicine Clinical Practice and Compliance – United States
77       Sleep Medicine Clinical Practice and Compliance – Europe
78       Introduction
79       Performance Deficits During Sleep Loss and Their Operational Consequences
80       Sleep and Sleep Disorders in Operational Settings
81       Shift Work, Shift-Work Disorder, Jet Lag, and Jet lag Disorder
82       Fatigue Countermeasures
83       Sleep, Sleepiness, and Performance Prediction Modeling
84       Fatigue Risk Management Systems
85       Safety Cases and Assessing Alternative Means of Regulatory Compliance in Fatigue Risk Management
86       Fatigue Proofing
87        Sleep and Athletic Performance
88        Assessment of the Occupational Sleep Medicine Field
89        Advances in Insomnia Pathophysiology and Treatment: An Introduction
90        Insomnia: Epidemiology, Risk Factors, & Health Disparities
91        Etiology and Pathophysiology of Insomnia
92        Pediatric Insomnia and its Developmental Trajectories
93        Insomnia Diagnosis, Assessment and Evaluation
94        Insomnia with Short Sleep Duration and Multidimensional Sleep Health
95        Behavioral Treatment I – Therapeutic Approaches and Implementation
96        Behavioral Treatment II – Efficacy, Effectiveness and Dissemination
97        Behavioral Treatment III – Digital and Telehealth Approaches
98        Pharmacological Treatment I – Therapeutic Approaches and Implementation
99        Pharmacological Treatment II – Efficacy, Effectiveness and Contraindications
100      SEQUENCED AND COMBINED PSYCHOLOGICAL AND PHARMACOLOGICAL TREATMENTS FOR INSOMNIA
101      Introduction
            Introduction
102      Parkinsonism
103      Sleep-Wake Disturbances and Stroke
104      Sleep and Neuromuscular Diseases
105      Alzheimer Disease and Other Dementias
106      Epilepsy
107      Sleep and Headache
108      Sleep Disorders after Traumatic Brain Injury
109      Autoimmune disorders (autoimmune encephalitides and MS)
110      Central Disorders of Hypersomnolence
            Introduction
111      Narcolepsy: Pathophysiology and Genetic Predisposition
112      Narcolepsy: Diagnosis and Management
113      Idiopathic Hypersomnia
114      Kleine-Levin Syndrome
115      Parasomnias-Overview and Approach
116      Disorders of Arousal
117      Sleep-Related Eating Disorder
118      REM Sleep Behavior Disorder
119      Nightmares and Dream Disturbances
120      Other Parasomnias
121      Restless Legs Syndrome and Periodic Limb Movements During Sleep
122      Movement Disorders in Sleep (other than PLMS)
123      Introduction
124      Central Sleep Apnea: Definitions, Pathophysiology, Genetics, and Epidemiology
125      Central Sleep Apnea: Diagnosis and Management
126      Anatomy and Physiology of Upper Airway Obstruction
127      Snoring and Pathologic Upper Airway Resistance Syndromes
128      Obstructive Sleep Apnea: Heritable Phenotypes and Genetics
129      Deep Phenotyping Across Diagnostic and Therapeutic Continuum of OSA
130      Clinical and Physiologic Heterogeneity of Obstructive Sleep Apnea
131      Obstructive Sleep Apnea: Clinical Features, Evaluation, and Principles of Management
132      Positive Airway Pressure Treatment for Obstructive Sleep Apnea
133      Pharmacological Treatments for Sleep Apnea Syndromes
134      Alternative strategies to management of Sleep Disordered Breathing
135      Brain Health in Sleep Apnea
136      Obstructive Sleep Apnea and Metabolic Disorders
137      Overlap Syndromes of Sleep and Breathing Disorders
138      Obesity-Hypoventilation Syndrome
139      Obstructive Sleep Apnea, Obesity, and Bariatric Surgery
140      Advanced modes of positive pressure therapy for sleep-disordered breathing
141      Sleep and Breathing at High Altitude
142      Evolution of sleep disordered breathing across the adult years
143      Introduction
144      Sleep-Related Cardiac Risk
145      Cardiac Arrythmogenesis During Sleep: Mechanisms, Diagnosis, and Therapy
146      Cardiovascular Effects of Sleep-Related Breathing Disorders
147      Systemic and Pulmonary Hypertension in Obstructive Sleep Apnea
148      Coronary Artery Disease and Obstructive Sleep Apnea
149      Heart Failure
150      Stroke/TIA and SDB
151      Insomnia and CVD
152      Introduction
            Introduction
153      Sleep and Cancer across the Lifespan
154      Fibromyalgia and Chronic Fatigue Syndromes
155      Endocrine Disorders
156      Pain and Sleep
157      Sleep in Chronic Kidney Disease
158      Sleep in the Critically Ill Patient
159      Peri-operative Sleep Medicine
160      Sleep and GI
160      Sleep in Chronic Respiratory Failure
161      Introduction
162      Stress and Sleep
162      Emotion and Sleep
            Introduction
163      Anxiety Disorders
164      Mood Disorders
165      Schizophrenia and Sleep
166      Substance Abuse
167      Dentistry and Otorhinolaryngology in Sleep Medicine: below the brain and above the larynx
168      Oronasopharyngeal growth & Skeletal Malformations
169      Sleep Bruxism: Definition, Prevalence, Etiology and Mechanisms
170      Sleep Bruxism: Diagnostic Considerations
171      Management of sleep bruxism: psychological, dental, and medical approaches in adults
172      Orofacial Pain/TMD in Relation to Sleep Bruxsim and Breathing Disorders
173      Oral Appliances for Sleep-Disordered Breathing
174      Anesthesia in Upper Airway Surgery
175      Upper airway surgery to treat SBD
176      Pharmacotherapy, Complementary, and Alternative Medicine for Sleep Bruxism
177      Overview
178      SLEEP-RELATED BREATHING DISORDERS IN CHILDREN
179      Neuromuscular disorders: Muscular Dystrophy, Spinal Muscular Atrophy, Mitochondrial Disorders, Myasthenia Gravis, Spina Bifida/Chiari Malformation, Cerebral Palsy,   Myotonic Dystrophy, Seizure Disorders
180     Transitional Care for Adolescents with Narcolepsy and other central disorders of hypersomnolence
181     Congenital Heart Disease
182     SLEEP IN INTERSEX AND TRANSGENDER INDIVIDUALS
183     Introduction
           Introduction
184     Sex Effects and Differences in Circadian Rhythms and Sleep
184     Syndromes Associated with Developmental Delays: Down syndrome, Marfan's syndrome, Other
185     The Menstrual Cycle, Sleep and Circadian Rhythms
186     Sleep and Sleep Disorders Associated with Pregnancy
187     Sleep Disordered Breathing during Pregnancy
188     Postpartum Period and Early Parenthood
189     Sleep and Menopause
190     Introduction
191     Psychiatric and Medical Comorbidities and Effects of Medications in Older Adults
192     Introduction
192     Obstructive Sleep Apnea in Older Adults
193     Insomnia in Older Adults
194     Circadian Rhythms in Older Adults
195     Sleep in Long-Term Care Settings
196     Section Introduction: Polysomnography and beyond
197     Sleep stage scoring
198     CNS Arousals & Cyclic Alternating Patterns
199     Neurologic Monitoring Techniques
200     Monitoring Techniques for Evaluating Suspected Sleep-Disordered Breathing
201     Sleep Telemedicine and Remote PAP Adherence Monitoring
202     Cardiopulmonary Coupling
203     Pulse Wave Analysis
204     Recording and Scoring Sleep-related Movements
205     Home Sleep Testing for Sleep Related Breathing Disorders
206     Consumer sleep tracking: ANSI/CTA performance standards
206     Consumer Sleep
207     Evaluating Sleepiness and Fatigue
208     THE ASSESSMENT OF INSOMNIA
209     Surveys, Sampling, and Polling Methods for Sleep and Public Health
210     Techniques for Clinical Assessment of Circadian Rhythm Disorders
211     Actigraphy Methods and Technical Issues
212     Imaging
213     Sleep and Covid