Cell Biology,4/e > Cell Biology

Accessible and user-friendly, Cell Biology, 4th Edition, provides a strong foundation for students entering health care career paths as well as higher level research areas. Clear, readable text and high-quality, detailed illustrations help readers quickly grasp challenging content—all focusing on cellular processes without delving into molecular processes. Drs. Thomas D. Pollard, William C. Earnshaw, Jennifer Lippincott-Schwartz, and author/illustrator Dr. Graham Johnson have thoroughly updated this popular text to ensure its relevance for students in biology, biotechnology, medicine, and pathophysiology, covering key principles of cellular function and explaining how molecular defects lead to cellular dysfunction and cause human disease.
Balances depth of detail with clear, readable explanations, providing a concise but comprehensive overview of this complex topic.    
An intuitive chapter flow leads with genome organization, gene expression, and RNA processing as a foundation for understanding cellular interactions and cell physiology.
Brings cellular biology to life for students in clinically focused programs, as breakthroughs in areas like gene editing, epigenetics, and the understanding of the microbiome continue to grow in clinical application.
Features unique illustrations with realistic proportions and relationships, including many new instructive illustrations— from structure of volume-regulated LRRC8 Cl -1 channel and generation of circular RNAs from introns … to deadenylation cycles and assembly of SARS CoV-2).
Covers new topics such as optogenetics and super resolution fluorescence microscopy; predicting 3D protein structure; gene expression profiling by single-cell RNA sequencing; protein misfolding and human disease; mechanism of CFTR and new drugs to treat cystic fibrosis; new insights on carriers and channels and their clinical implications; mitochondrial genomes from sperm; and biogenesis of lipid droplets and lipid transfer between organelles.
Uses real examples to illustrate key cell biology concepts, includes beneficial cell physiology coverage, and relates cell biology to pathophysiology and medicine.
Enhanced eBook version included with purchase. Your enhanced eBook allows you to access all of the text, figures, and references from the book on a variety of devices.

Front Matter/Back Matter/Section Openers
1 Introduction to Cells
2 Evolution of Life on Earth
3 Molecules: Structures and Dynamics
4 Biophysical Principles
5 Macromolecular Assembly
6 Research Strategies
7 Chromosome Organization
8 DNA Packaging in Chromatin and Chromosomes
9 Nuclear Structure and Dynamics
10 Gene Expression
11 Eukaryotic RNA Processing
12 Protein Synthesis and Folding
13 Membrane Structure and Dynamics
14 Membrane Pumps
15 Membrane Carriers
16 Membrane Channels
17 Membrane Physiology
18 Posttranslational Targeting of Proteins
19 Mitochondria, Chloroplasts, Peroxisomes
20 Endoplasmic Reticulum
21 Mechanisms of Vesicular Trafficking
22 Secretory Membrane System and Golgi Appartus
23 Endocytosis and Endosomal Membrane System
24 Processing and Degradation of Cellular Components
25 Plasma Membrane Receptors
26 Protein Hardware for Signaling
27 Second Messengers
28 Integration of Signals
29 Cells of the Extracellular Matrix and Immune System
30 Extracellular Matrix Molecules
31 Cellular Adhesion
32 Intercellular Junctions
33 Connective Tissues
34 Actin and Actin-Binding Proteins
35 Microtubules and Centrosomes
36 Intermediate Filaments
37 Motor Proteins
38 Intracellular Motility
39 Cellular Motility
40 Muscles
41 Introduction to the Cell Cycle
42 G1 Phase and Regulation of Cell Proliferation
43 S Phase and DNA Replications
44 G2 Phase, Responses to DNA Damage, and Control of Entry into Mitosis
45 Mitosis
46 Cytokinesis
47 Meiosis
48 Programmed Cell Death
 Cell SnapShots