Make sure you are thoroughly prepared to work in a clinical laboratory. Rodak’s Hematology: Clinical Principles and Applications, 7th Edition uses hundreds of full-color photomicrographs to help you understand the essentials of hematology and hemostasis. This new edition details the parts and functions of the cell; shows how to accurately identify cells; covers normal hematopoiesis through diseases of erythroid, myeloid, lymphoid, and megakaryocytic origins; and simplifies hemostasis and thrombosis concepts and disorders. Easy to follow and understand, this book also covers key topics, including working in the hematology and hemostasis laboratory; complementary testing areas such as flow cytometry, cytogenetics, and molecular diagnostics; and laboratory testing of blood cells and body fluid cells.
New to this edition
NEW! Chapter on Patient Safety in Hematology and Hemostasis.
NEW! Section on hematology and hemostasis in transgender populations.
UPDATED! White blood cell chapters are current with the 2022 World Health Organization (WHO) Classification of Haematolymphoid Tumours.
NEW! Changes in laboratory results associated with COVID-19 and other viral infections.
NEW! Content and figures on plasma transport, cell communication, and signal transduction.
NEW! Coverage of CRISPR technology for treatment of hemoglobinopathies and thalassemia.
UPDATED! Major revision of the Automated Blood Cell Analysis chapter.
Key Features
Content throughout the text reflects the latest information on hematology and hemostasis.
Hematology and hemostasis instruments are described, compared, and contrasted.
More than 700 full-color illustrations and photomicrographs make it easier to visualize hematology concepts and show what you’ll encounter in the laboratory.
Instructions for laboratory procedures include detailed figures and sources of errors.
Case studies in each chapter provide opportunities to apply hematology concepts to real-life scenarios.
Hematology and hemostasis reference intervals are listed on the inside front and back covers for quick reference.
Bulleted chapter summaries make it easy for you to review important points.
Learning objectives begin each chapter and indicate what you should achieve, with review questions appearing at the end.
Appendices provide easy access to a list of key formulas, abbreviations, and a detailed glossary to complement learning.
Author Information
Edited by Elaine M. Keohane, PhD, MLS, Professor, Department of Clinical Laboratory Sciences University of Medicine and Dentistry of New Jersey School of Health-Related Professions Newark, New Jersey; Michelle Butina, PhD, MLS(ASCP)CM, Associate Professor; Vice Chair of the Clinical Laboratory Sciences;Director of the Medical Laboratory Science Program;Department of Pathology, Anatomy and Laboratory Medicine West Virginia University; Kamran M. Mirza, MD, PhD, FCAP, FASCP, MLS(ASCP)CM, Associate Professor of Pathology and Laboratory Medicine Medical Education, and Applied Health Sciences; Vice-Chair of Education Department of Pathology and Laboratory Medicine; Program Director Hematopathology Fellowship; Founding Program Director MS in Medical Laboratory Science; Stritch School of Medicine and Parkinson School of Health Sciences and Public Health Loyola University Chicago and Jeanine M. Walenga, PhD, MLS (ASCP)HCM, Professor, Thoracic & Cardiovascular Surgery and Pathology Clinical Coagulation Laboratory Director Loyola University Medical Center Maywood, Illinois
1. An Overview of Clinical Laboratory Hematology
2. Quality Assurance in Hematology and Hemostasis Testing
3. Cellular Structure and Function
4. Hematopoiesis
5. Erythrocyte Production and Destruction
6. Erythrocyte Metabolism and Membrane Structure and Function
7. Hemoglobin Metabolism
8. Iron Kinetics and Laboratory Assessment
9. Leukocyte Development, Kinetics, and Functions
10. Platelet Production, Structure, and Function
11. Manual, Semiautomated, and Point-of-Care Testing and Hematology
12. Automated Blood Cell Analysis
13. Examination of the Peripheral Blood Film and Correlation with the Complete Blood Count
14. Bone Marrow Examination
15. Body Fluid Analysis in the Hematology Laboratory
16. Anemias: Red Blood Cell Morphology and Approach to Diagnosis
17. Disorders of Iron Kinetics and Heme Metabolism
18. Anemias Caused by Defects of DNA Metabolism
19. Bone Marrow Failure
20. Introduction to Increased Destruction of Erythrocytes
21. Intrinsic Defects Leading to Increased Erythrocyte Destruction
22. Extrinsic Defects Leading to Increased Erythrocyte Destruction – Nonimmune Causes
23. Extrinsic Defects Leading to Increased Erythrocyte Destruction – Immune Causes
24. Hemoglobinopathies (Structural Defects in Hemoglobin)
25. Thalassemias
26. Non-Malignant Leukocyte Disorders
27. Intro to Hematologic Malignancies
28. Flow Cytometric Analysis in Hematologic Disorders
29. Molecular Diagnostics in the Clinical Laboratory
30. Cytogenetics
31. Acute Leukemias
32. Myeloproliferative Neoplasms
33. Myelodysplastic Syndromes
34. Mature Lymphoid Neoplasms
35. Normal Hemostasis and Coagulation
36. Hemorrhagic Disorders and Laboratory Assessment
37. Qualitative Disorders of Platelets and Vasculature
38. Thrombocytopenia and Thrombocytosis
39. Thrombotic Disorders and Laboratory Assessment
40. Antithrombotic Therapies and Their Laboratory Assessment
41. Laboratory Evaluation of Hemostasis
42. Hemostasis and Coagulation Instrumentation
43. Hematology and Hemostasis in the Pediatric, Geriatric, and Pregnant Populations
Appendix A: Abbreviations
Appendix B: List of Formulas
Appendix C: Answers
Appendix D: Glossary
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