Kidney Transplantation - Principles and Practice, 9/e > Nephrology

A must-have resource for all members of the transplant team, Kidney Transplantation: Principles and Practice, 9th Edition, provides comprehensive, up-to-date information on every aspect of this complex field. Drs. Stuart J. Knechtle and Lorna P. Marson, along with a global team of internationally renowned surgeons and nephrologists, offer balanced coverage of both surgical techniques and medical considerations related to kidney transplantation. With updates from cover to cover, this core reference delivers the practical guidance you need to achieve optimal outcomes in both adults and children.

New to this edition

New chapter on xenotransplantation. This area is under active clinical investigation now and it seems likely to move forward in the next few years.
New chapter on future developments, including cell therapies (this could possibly be merged with the xenotranplantation chapter).
New chapter on defining metrics of success following transplantation.
New chapter on COVID in renal transplantation.
Added discussion of normothermic regional perfusion to the discussion of DCD organ donation and ethics of transplantation (this is a new and evolving approach to organ donation).
Expanded biomarkers section to include information on iBox (The first universal algorithm for predicting the risk of kidney transplant loss).
Modified History chapter
Additional intraoperative video clips (about 10-15 new)
New authorship for select chapters
 Key Features

Offers state-of-the-art coverage of all areas of kidney transplantation such as preservation of kidneys; mechanisms of rejection and the induction of tolerance; techniques of laparoscopic live donor nephrectomy; and immunosuppression.
Contains up-to-date outcomes data and analysis of the evidence supporting current practice in the field.
Includes new chapters on xenotransplantation and COVID-19 in renal transplantation.
Adds new information on normothermic regional perfusion to the discussion of DCD organ donation and ethics of transplantation, and new information on iBox (the first universal algorithm for predicting the risk of kidney transplant loss) to the biomarkers section.
Provides relevant, up-to-date information on kidney transplant for all members of the transplant team, with practical information on applied science, clinical information, and surgical procedures.
Features intraoperative videos and hundreds of superb illustrations to help readers visualize key concepts and nuances of renal transplantation.
Covers each major immunosuppressive drug in individual chapters, and provides a reference list of all randomized trials for convenient access to critical information.
An eBook version is included with purchase. The eBook allows you to access all of the text, figures and references, with the ability to search, customize your content, make notes and highlights, and have content read aloud. Additional digital ancillary content may publish up to 6 weeks following the publication date.

Author Information

Edited by Stuart J. Knechtle, MD, William R. Kenan, Jr. Professor of Surgery; Executive Director, Duke Transplant Center, Adjunct Professor, Department of Medicine, Duke University School of Medicine, Durham, North Carolina; Lorna P. Marson, MD, Senior Lecturer in Transplant Surgery, University of Edinburgh and Honorary Consultant Transplant Surgeon, Royal Infirmary of Edinburgh

1. Kidney Transplantation: A History
2. Immunology of Rejection
3. End-stage Renal Failure and Renal Replacement Therapy
4. The Recipient of Renal Replacement
5. Access of Renal Replacement Therapy
6. Brainstem Death
7. The Donor and Donor Nephrectomy
8. Laparoscopic Donor Nephrectomy
9. Renal Preservation
10. HLA Matching and Cross matching
11. Surgical Techniques of Renal Transplantation
12. Transplantation and the Abnormal Bladder
13. Anaesthesia in Renal Transplantation
14. The Early Course of a Patient with a Kidney Transplant
15. Azathioprine and Steroids
16. Cyclosporine
17. Tacrolimus
18. Experimental and Clinical Experience with Mycophenolate Mofetil
19. Sirolimus
20. Antilymphocyte Globulin and Monoclonal Antibodies
21. Other Forms of Immunosuppression
22. Total Lymphoid Irradiation
23. Approaches to the Induction of Tolerance
24. Histopathology of Renal Allograft Rejection
25. Immunohistology of the Transplanted Kidney
26. Transplant Cytology
27. Chronic Renal Allograft Failure
28. Vascular and Lymphatic Complications After Renal Transplantation 29. Urological Complications After Renal Transplantation
30. Cardiovascular Complications of Transplantation
31. Infectious Complications After Renal Transplantation
32. Liver Complications After Renal Transplantation
33. Neurological Complications after Renal Transplantation
34. Skin Lesions in Renal Transplant Patients
35. Cancer in Dialysis and Transplant Patients
36. Renal Transplantation for Diabetic Nephropathy
37. Paediatric Transplantation
38. Transplantation in Developing Countries
39. Results in Renal Transplantation
40. Psychological Aspects of Kidney Transplantation and Organ Donation 41. Ethics in Transplantation
42. Xenotransplantation of the Kidney
43. The Human Leukocyte Antigen (HLA) System and Nomenclature