Now with full-color illustrations throughout, dozens of new review questions, and state-of-the-art coverage of this fast-changing area, Pediatric Gastrointestinal and Liver Disease, 6th Edition, remains the leading text in the field. You’ll find definitive guidance on diagnosis and treatment from experienced editors Drs. Robert Wyllie, Jeffrey S. Hyams, and Marsha Kay, as well as globally renowned contributors who share their knowledge and expertise on complex issues
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Features an enhanced art program with full-color anatomical figures, clinical photos, and other illustrations throughout the text.
Includes a new chapter on fecal transplantation (FCT), covering donor and recipient screening, preparation, delivery, follow-up, and safety considerations, as well as investigative uses for FCT for disorders such as IBD, IBS, and D-lactic acidosis.
Prepares you for certification and recertification with more than 400 board review-style questions, answers, and rationales – 30% new to this edition.
Includes detailed diagrams that accurately illustrate complex concepts and provide at-a-glance recognition of disease processes.
Contains numerous algorithms that provide quick and easy retrieval of diagnostic, screening, and treatment information.
Provides up-to-date information on indigenous flora and the gut microbiome and clinical correlations to treatment, as well as advancements in liver transplantation including split liver transplantation (SLT) and living donor liver transplantation (LDLT).
Details key procedures such as esophagogastroduodenoscopy and related techniques; colonoscopy and polypectomy; endoscopic retrograde cholangiopancreatography; capsule endoscopy and small bowel enteroscopy; gastrointestinal pathology; and more
Enhanced eBook version included with purchase. Your enhanced eBook allows you to access all of the text, figures, and references from the book on a variety of devices.
1 Biologic Aspects of Gastrointestinal Function
1. Development of the Gastrointestinal Tract
Jaime Belkind-Gerson
2. Basics Aspects of Digestion and Absorption
Ghassan T. Wahbeh and Nicole Green
3. Bile Acid Physiology and Alterations in the Enterohepatic Circulation
James E. Heubi
4. The Gut Microbiome in Pediatrics
Gail A. M. Cresci and Jonathan E. Teitelbaum
5. Gastrointestinal Mucosal Immunology and Mechanisms of Inflammation
Simon Murch
2 Clinical Problems
6. Chroic Abdominal Pain of Childhood and Adolescence
Miguel Saps and Peter L. Lu
7. Approach to the Child with a Functional Gastrointestinal Disorder
Paul E. Hyman and Neha R. Santucci
8. Vomiting and Nausea
Jasmeet Mokha
9. Diarrhea
Peter Townsend and Melissa Fernandes
10. Colic and Gastrointestinal Gas
Sandeep K. Gupta
11. Functional Constipation and Incontinence
Marc A. Benninga
12. Failure to Thrive
Rebecca N. Cherry
13. Gastrointestinal Hemorrhage
Petar Mamula, Joel Aaron Friedlander and Benjamin Sahn
14. Obesity
Joseph Skelton and Gail Cohen
15. Eating Disorders in Children and Adolescents
Ellen S. Rom
16. Jaundice: Unconjugated Hyperbilirubinemia
Cara Mack and Glenn R. Gourley
17. Ascities
David Piccoli and Henry Lin
18. Caustic Ingestion and Foreign Bodies
Michael A. Manfredi
3 The Esophagus
19. Developmental Anatomy and Physiology of the Esophagus
Kristin Nicole Fiorino
20. Congenital Malformations of the Esophagus
Arnold G. Coran, Shaun Michael Kunisaki and Steven W. Bruch
21. Gastroesophageal Reflux
Yvan Vandenplas
22. Achalasia and Other Motor Disorders
Manu R. Sood and Diana G. Lerner,
23. Other Diseases of the Esophagus
Franziska Mohr and Katherine Baldwin
4 The Stomach
24. Developmental Anatomy and Physiology of the Stomach
Christina S. Wills
25. Congenital Anomalies and Surgical Disorders of the Stomach
Federico G. Seifarth
26. Gastritis, Gastropathy, and Ulcer Disease
Quin Y. Liu and Travis Piester
27. Helicobacter Pylori in Childhood
Séamus Hussey and Eileen Crowley
28. Gastric Motility Disorders
Carlo Di Lorenzo and Peter L. Lu
29. Bezoars
Adam G. Mezoff and Ethan Mezoff
5 The Small and Large Intestine
30. Anatomy and Physiology of the Small and Large Intestines
Rose Lee and Ethan Mezoff
31. Maldigestion and Malabsorption
Steven H. Erdman and Tracy R. Ediger
32. Protracted Diarrhea
David Piccoli and Lindsey Albenberg
33. Protein-Losing Enteropathy
David Piccoli
34. Celiac Disease
Riccardo Troncone and Renata Auricchio
35. Short Bowel Syndrome
Robert S. Venick
36. Small Bowel Transplant
Kareem Abu Elmagd and Girlanda Raffaelle
37. Allergic and Eosinophilic Gastrointestinal Disease
Chris A. Liacouras, Rajitha Devadoss Venkatesh, Jonathan E. Markowitz and Lindsay Marie Moye
38. Infectious Diarhea
Mitchell B. Cohen and David Galloway
39. Enteric Parasites
Dorsey M. Bass and Rachel Ruiz
40. Gastrointestinal Manifestations of Primary Immunodeficiency - Gastrointestinal Complications of Secondary Immunodeficiency Syndromes
Athos Bousvaros and Ivan Fuss
41. Pediatric Polyposis Syndromes
Warren Hyer
42. Crohn's Disease
Jennifer L. Dotson and Brendan Boyle
43. Ulcerative Colitis in Children and Adolescents
James F. Markowitz and Samuel Bitton
44. Chronic Intestinal Pseudo-Obstruction
Hayat Mousa, Maheen Hassan and Peter L. Lu
45. Neonatal Necrotizing Enterocolitis
Ricardo J. Rodriguez and Sabine Iben
46. Disorders of the Anorectum: Fissures, Fistulas, Prolapse, Hemorrhoids, Tags
Marian D. Pfefferkorn and Sharon McPheeters
47. Neoplasms of the Gastrointestinal Tract
Jacob A. Kurowski and Praveen Kumar Conjeevaram Selvakumar
48. Neoplasms of the Liver
Karen F. Murray and Hengqi (Betty) Zheng
49. Other Diseases of the Small Intestine and Colon
Orhan Atay
50. Appendicitis
Michael Gerard Caty
6 Pediatric Surgical Disorders
51. Intussusception in Infants and Children
Todd Ponsky and Sophia Abdulhai
52. Inguinal Hernias and Hydroceles
Christine Rader and Jacob Campbell
53. Meckel's Diverticulum and Other Omphalomesenteric Duct Remnants
Brendan T. Campbell and Jennifer Brewer
54. Hirschsprung's Disease
Jacob C. Langer
55. Imperforate Anus
Andrea Bischoff and Alberto Pena
56. Abnormal Rotation and Fixation of the Intestine
Thomas T. Sato and Eleanor H. Sato
57. Small and Large Bowel Stenosis and Atresias
Keith T. Oldham and Ruchi Amin
58. Newborn Abdominal Wall Defects
Jaimie D. Nathan and Stephanie Polites
59. Stomas of the Small and Large Intestine
Anthony L. Deross
7 Gastrointestinal Procedures
60. Esophagogastr Oduodenoscopy, and Related Techniques
Marsha Kay, Robert Wyllie III and Natalie Bhesania
61. Colonoscopy, Polypectomy, and Related Techniques
Marsha Kay, Robert Wyllie III and Jessica Barry
62. Endoscopic Retrograde Cholangiopancreatography
Douglas G. Adler and Atif Saleem, Mounif El-Youssef, Todd H. Baron
63. Capsule Endoscopy and Small Bowel Enteroscopy
Bradley Barth and Isabel ROJAS
64. Gastrointestinal Motility Procedures
Samuel Nurko
65. Gastrointestinal Pathology
Robert E. Petras, Thomas Plesec and Erica C. Savage
66. Liver Pathology
Thomas Plesec and Michael Cruise
8 The Liver and Bile Ducts
67. Developmental Anatomy and Physiology of the Liver and Bile Ducts
Sanjiv Harpavat
68. Neonatal hepatitis
Vicky Lee Ng and Mohit Kehar
69. Biliary Atresia and Neonatal Disorders of the Bile Ducts
Giorgina Mieli-Vergani and Nedim Hadzic
70. Pediatric Cholestatic Liver Disease with Genetic Etiology
Karan McBride Emerick and Kathleen M. Loomes
71. Mitochondrial Hepatopathies: Disorders of Fatty Acid Oxidation and the Respiratory Chain
Patrick McKiernan
72. Abronmalities of Hepatic Protein Metabolism
Fayez K. Ghishan
73. Abnormalities of Carbohydrate Metabolism and the Liver
Shikha S. Sundaram
74. Nonalcoholic Fatty Liver Disease
Ariel Feldstein
75. Acute and Chronic Hepatitis
Maureen M. Jonas and Rima Fawaz
76. Portal Hypertension
Estella Alonso and Lee M. Bass
77. Liver Failure
Suz Warner and Deidre Kelly
78. Liver Transplantation in Children
Koji Hashimoto, Bijan Eghtesad and John Fung
79. Diseases of the Gallbladder
Douglas S. Fishman and Frances Lee
9 The Pancreas
80. Pancreatic Development
Sohail Z. Husain and John Eisses
81. Cystic Fibrosis and Congenital Anomalies of the Exocrine Pancreas
Joel R. Rosh, Sarah Shrager Lusman and Nadia Ovchinsky
82. Pancreatitis
Maisam Abu-El-Haija and David Vitale
83. Total Pancreatectomy with Autoislet Transplantation, and Pancreatic Allotransplantation
R. Matthew Walsh
84. Secretory Neoplasms of the Pancreas
Allan Siperstein
85. Infant and Toddler Nutrition
Susan S. Baker and Robert D. Baker
10 Nutrition
86. Nutritional Assessment
Kate A. Samela
87. Tubes for Enteric Access
Donald E. George and Sina Ogholikhan
88. Parenteral Nutrition
Maria R. Mascarenhas and Jennifer Panganiban
89. Enteral Nutrition
Neal S. LeLeiko and Carolina S. Cerezo
90. Management of Diarrhea
David Devadason
91. Effects of Digestive Diseases on Bone Metabolism
Francisco A. Sylvester
92. Nutrition and Feeding for Children with Developmental Disabilities
Ryann Mayer and Donna Zeiter
93. Fecal Transplant
Zev Davidovics
94. Questions
Eugene Vortia
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